Yeon-Woo Heo, MD, Jae Joon Jeon, MD, Min Chul Ha, MD, et al, Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea,

A groundbreaking study examining nearly 7 million participants has uncovered a significant link between COVID-19 infection and the development of autoimmune disorders. The research shows that COVID-19 survivors face a 43% higher risk of developing various autoimmune conditions, even months after recovery.

COVID-19 and Autoimmune Risk

The study tracked over 3.1 million people who had COVID-19 and 3.7 million who did not, monitoring them for more than six months. This extensive research revealed that COVID-19 survivors showed increased vulnerability to several autoimmune conditions, with risk levels varying based on factors such as age, gender, and severity of initial infection.

Among the most frequently observed conditions, five stood out prominently. Rheumatoid arthritis showed a 9% increased risk, while systemic lupus saw a 14% higher occurrence rate. Crohn’s disease demonstrated a particularly concerning 35% increase. Visible conditions such as alopecia (hair loss) and vitiligo (skin depigmentation) showed 11% higher risk rates compared to those who never had COVID-19.

Prevention and Management

The research findings emphasize the importance of long-term healthcare monitoring for COVID-19 survivors. Those who experienced severe cases, particularly during the Delta variant period, showed higher risks of developing autoimmune conditions. Medical professionals are advised to maintain vigilant monitoring of post-COVID patients, especially those who experienced severe infections.

Original article: Long-Term Risk of Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19.