The NO Secrets, front cover: a tree rooted in Greek temple ruins
16 Practips Nitric Oxide Solutions From Ancient Medicine
The
NO
Secrets
Nitric Oxide · The Master Molecule

Why your energy and vitality are declining, and how ancient civilizations solved it without pills or prescriptions.

Publishing in two weeks

The premise

Sixteen civilizations found the same molecule. None of them knew what it was.

Egyptian foremen paid in silver for garlic. Greek Olympians were crowned in celery. Persian physicians prescribed pomegranate for what they called hardening vessels. Tibetan monks hummed. Venetian merchants ate rocket at sea. Each tradition was dismissed as folklore.

Then in 1998, Robert Furchgott, Louis Ignarro and Ferid Murad won the Nobel Prize in Physiology or Medicine for discovering that nitric oxide is a signalling molecule in the cardiovascular system. It relaxes blood vessels, lowers blood pressure and moves oxygen. And it is exactly what every one of those traditions was quietly switching on.

This book is the map: 16 protocols, each one traced from the culture that found it to the peer-reviewed research that explains it, and each one written to be used tomorrow morning.

1550 BCE

The Ebers Papyrus lists garlic in 22 remedies, prescribed for circulation and for strengthening the heart.

520 BCE

Victors at the Nemean Games are crowned with wild celery. Historians read it as symbolism for the next 2,400 years.

400 BCE

Yogic practitioners document that nasal breathing calms and mouth breathing agitates. They have no laboratory, only generations of observation.

150 BCE

Persian physicians prescribe pomegranate for hardening vessels. The dose they land on is one fruit daily.

1998

The Nobel Prize. Nitric oxide is identified as the molecule controlling the cardiovascular system. The mechanism behind every entry above finally has a name.

2009

The University of Exeter shows beetroot juice cuts the oxygen cost of exercise. By 2012 nutritionists are calling London the beetroot Olympics.

2014

Edinburgh finds that UVA on skin releases stored nitric oxide and drops blood pressure, entirely independently of vitamin D.

Today

The research is published, the mechanism is understood, and almost none of it has reached your appointment.

What is inside

Sixteen protocols

Read in any order. Each chapter stands alone: history, mechanism, evidence, protocol.

Beetroot

Eastern Europe · Borscht to podium

Dietary nitrate, converted by the bacteria on your tongue.

Nasal breathing

Yogic India · 400 BCE

Your sinuses are a nitric oxide factory. Mouth breathing delivers none.

Arugula

Renaissance Venice · 1447

The densest dietary nitrate on the shelf, for the price of a coffee.

Cacao

Mesoamerica · 600 BCE

Epicatechin tells the vessel lining to release nitric oxide. Mayan healers called it opening the heart.

Humming

Rongbuk Monastery · 16,340 ft

Vibration moves the gas out of the sinuses. Swedish researchers measured a 15-fold jump.

Wild greens

Crete · Shepherds at 80

Fifty-five wild species, eaten daily, at up to ten times the nitrate of supermarket produce.

Pomegranate

Persia · 150 BCE

Does not make nitric oxide. Protects the nitric oxide you already made.

Garlic

Giza · 1550 BCE

Crush it, then wait. Cook it too soon and you destroy the compound you came for.

Sunlight

Egypt and Greece · Solar temples

Your skin stores nitrite at ten times blood levels. UVA lets it go.

The oral microbiome

Ayurveda · 3,000 years of scraping

The bacteria antiseptic mouthwash kills are the ones doing the conversion.

Watermelon

Nile Valley · 3500 BCE

Citrulline skips the liver. The white rind is the part worth keeping.

Celery

Nemean Games · 520 BCE

Nitrate, plus phthalides investigated for relaxing vessel walls. The wreath was not decoration.

Chia

Aztec relay runners · 1570s

Fibre and plant omega-3s. The vascular benefit is real, the nitric oxide link is indirect.

Moringa

Ayurvedic India · 2000 BCE

Called the plant that pierces disease. Nutritionally dense, though not the most direct route.

Maca

Junín plateau · 14,232 ft

Grown where little else survives. Traditional use is strong, the mechanism is still thin.

Fermented tea

Shan highlands · 12th century

Polyphenols that help the vessel lining make its own. A monsoon accident, kept for 800 years.

Nature has provided many pathways to support this remarkable molecule, and no single food or intervention is a miracle cure. Dr. Philip McMillan, from the foreword

Why this one is different

Every chapter closes with a clinical perspective that argues with the chapter. Where the evidence is thin, it says so: maca gets marked down, chia is told plainly that its benefit probably is not nitric oxide at all, and the more dramatic arterial claims around pomegranate are called early rather than settled.

The cautions are in there too, because a food that behaves like a drug interacts like one. Beetroot stacked on a nitrate medication. Garlic before surgery. Mouthwash weighed against real gum disease. Moringa against thyroid function.

Written by Dr. Philip McMillan, a physician and researcher whose work on nitric oxide in the nose and paranasal sinuses began during the COVID-19 pandemic and led to the first book, Humming Heroes, with co-author John McMillan.

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This book is not intended as a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or another qualified health provider before undertaking any diet, exercise, breathing technique or other health-related programme described in this work. Certain techniques may be contraindicated for specific medical conditions. Individual results vary.

The NO Secrets Dr. Philip McMillan & John McMillan Published by Lumienta Limited, London Vejon Health Design preview: signup form pending Beehiiv connection